Research Gaps
Automated analysis of 748 remedies and 374 conditions to identify where evidence is missing or insufficient.
57
Critical Gaps
11
High Priority
8
Medium
76
Total Gaps
Saffron
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Chamomile
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Lavender
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Passionflower
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Folic Acid / Methylfolate
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Ginkgo Biloba
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Lion's Mane Mushroom
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Bacopa Monnieri
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Ginseng
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Vitex / Chaste Berry
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Reishi Mushroom
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Hawthorn
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Kudzu
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Skullcap
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Hops
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Saw Palmetto
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Devil's Claw
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Black Cohosh
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Red Clover
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Dong Quai
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Aloe Vera (Internal)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Cinnamon (Ceylon)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Turmeric (Curcuma longa)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Licorice / Yashtimadhu (Glycyrrhiza glabra)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Peppermint Oil (Enteric-Coated)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Feverfew
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Cranberry Extract
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Andrographis
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Apigenin
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Oregon Grape (Berberis)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Fisetin
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Pterostilbene
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Schisandra
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Moringa
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Goldenseal
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Uva Ursi (Bearberry)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Thyme
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Kanna (Sceletium tortuosum)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Calcium D-Glucarate
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Triphala
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Olive Leaf Extract
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Allicin (Garlic Extract)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Bilberry
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Folate (Vitamin B9 / Methylfolate)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Stinging Nettle (Leaf & Root)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Gotu Kola
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Jiaogulan (Gynostemma)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
White Willow Bark
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Astragalus Root
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Evening Primrose Oil
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Riboflavin (Vitamin B2)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Luteolin
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Naringenin
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Hesperidin
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Rutin (Quercetin-3-Rutinoside)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Indole-3-Carbinol (I3C)
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Magnolol
Missing interactions: Has CYP450 activity documented but ZERO drug interactions listed
Lemon Balm
High-use, low-evidence: Referenced by 6 conditions but evidence is EMERGING
Zinc
High-use, low-evidence: Referenced by 36 conditions but evidence is EMERGING
Rhodiola
High-use, low-evidence: Referenced by 10 conditions but evidence is EMERGING
Resveratrol
High-use, low-evidence: Referenced by 9 conditions but evidence is EMERGING
Quercetin
High-use, low-evidence: Referenced by 20 conditions but evidence is EMERGING
Green Tea Extract (EGCG)
High-use, low-evidence: Referenced by 7 conditions but evidence is EMERGING
Alpha-Lipoic Acid
High-use, low-evidence: Referenced by 19 conditions but evidence is EMERGING
L-Glutamine
High-use, low-evidence: Referenced by 9 conditions but evidence is EMERGING
Bone Broth Collagen
High-use, low-evidence: Referenced by 9 conditions but evidence is EMERGING
Aloe Vera (Internal)
High-use, low-evidence: Referenced by 12 conditions but evidence is PRELIMINARY
Cat's Claw
High-use, low-evidence: Referenced by 9 conditions but evidence is EMERGING
Galactorrhea
Under-served condition: Only 1 remedy linked - needs more research coverage
Hyperprolactinemia
Under-served condition: Only 1 remedy linked - needs more research coverage
Vaginismus / Pelvic Floor Dysfunction
Under-served condition: Only 0 remedy linked - needs more research coverage
Vulvodynia
Under-served condition: Only 0 remedy linked - needs more research coverage
Prostate Cancer (Herbal Adjunct)
Under-served condition: Only 1 remedy linked - needs more research coverage
Lewy Body Dementia Support
Under-served condition: Only 1 remedy linked - needs more research coverage
ALS / Motor Neuron Disease Support (Adjunct)
Under-served condition: Only 0 remedy linked - needs more research coverage
Autism Spectrum (Herbal Adjunct)
Under-served condition: Only 0 remedy linked - needs more research coverage