Natural Remedies

Amino Acid · 50-100mg 2-3x daily; start at 50mg at bedtime

Phytochemical Nootropic · Research not yet in human clinical trials - animal studies use 2–5mg/kg IP or oral. Available as research chemical/supplement: 25–50mg oral (highly experimental - limited human safety data). Natural food sources: fisetin-containing foods, herbs - much lower concentrations than needed for TrkB activation.

Cissampelos pareira

South American Herbalism · 1–3g dried root bark as decoction 2x daily; 2–4ml tincture 2x daily

Amino Acids · 1500–3000 mg/day in divided doses

Acorus calamus

Ayurvedic Nootropic · 0.5–1g powdered rhizome (US regulatory note: FDA banned beta-asarone-containing calamus as food additive in 1968 due to carcinogenicity concerns in rodents - use diploid variety from India with low beta-asarone, not triploid North American variety). Standardized diploid extract: 250–500mg twice daily.

Amino Acid / Nutrient · Internal: 1–2 tsp in water. External: paste with water applied to affected area.

Mineral · 500-1000mg between meals (2 hours away from food/meds)

Laricifomes officinalis

Medicinal Mushroom · 250–500 mg concentrated mycelium extract daily; historically used as ground conk in small doses (1–2 g) - large doses of agaric acid are toxic

Agave americana / A. tequilana

Indigenous Americas · Prebiotic fiber: 1–2 tablespoons agave inulin powder daily; traditional: pulque (fermented sap) - not medical dose

Agrimonia eupatoria

European Phytotherapy · 1-4g dried herb as tea 3x daily

Agrimonia eupatoria

European Phytotherapy · 2-4g dried herb as tea 3x daily; or gargle for sore throat

Artemisia argyi

Korean Hanbang · Moxibustion: processed moxa (mugwort cigars or cones) applied to acupoints - indirect moxa preferred. Internal: 3–9g dried leaves as decoction (used for dysmenorrhea, vaginal discharge); NOT for long-term internal use.

Akkermansia muciniphila

Probiotics & Gut Health · 100 million–10 billion cells/day (pasteurized form preferred)

Albizia julibrissin

Chinese Herbal Medicine · 6–12g dried bark decocted (traditional). Standardized extract: 500mg–1g twice daily. Tincture: 3–5mL twice daily. Takes 2–4 weeks for full antidepressant effects.

Nootropic · 500–2000mg daily in 1–2 divided doses. Alzheimer's adjunct: 1500–2000mg/day. Neuropathic pain: 1000–2000mg/day. General nootropic: 500–1000mg morning. Different from L-carnitine - do not substitute.

Allium sativum

Herbal Medicine · Stabilized allicin 180-900 mcg/day or 1 fresh clove crushed (wait 10 min before consuming)

Phytochemical · 600–1200 mg allicin-producing garlic extract daily (standardized to allicin yield 3600–5400 μg); or 300 mg stabilized allicin; AGE (Aged Garlic Extract) 2–4g daily

Aloe barbadensis

Herbal Medicine · 2–4 oz aloe vera juice daily (inner leaf gel only)

L-Alpha glycerylphosphorylcholine

Nootropics · 300–600 mg/day; up to 1200 mg/day for cognitive decline

Polyphenol / Antioxidant · 600–1200 mg daily

Fomes fomentarius

Medicinal Mushroom · 250–500 mg extract daily; traditionally used externally as wound compress or smoked as analgesic

Emblica officinalis

Ayurveda Immune/Rasayana · 3-6g powder daily; or fresh fruit/juice

Panax quinquefolius

Men's Health · 400mg–1g standardized extract (4% ginsenosides) twice daily. Traditional: 1–3g dried root decocted. Cycle: 3 weeks on, 1 week off.

Panax quinquefolius

TCM Yin Tonics · 3-6g daily; can be sliced and steeped

Anacyclus pyrethrum

Ayurvedic Medicine · 250–500mg root powder twice daily. Ayurvedic: 3–6g powder with milk. Standardized extract: 250mg (5:1) daily.

Andrographis paniculata

Herbal Extracts · 200 mg standardized extract (30% andrographolide) 2× daily during illness

Phytochemical · 200–400 mg andrographolide (standardized Andrographis paniculata extract 10–20% andrographolide) daily for immune support; higher for acute infection protocols (up to 1200 mg/day short-term)

Flavonoids · 50–100 mg before bed for sleep; up to 300 mg for other benefits

Digestive Bitters & Tonics · 1–2 tablespoons in water before meals; dilute to protect tooth enamel

Terminalia arjuna

Ayurveda Cardiac/Circulatory · 2-4g bark powder in milk daily; traditionally taken with honey